Chemistry of Nucleic Acids (De Gruyter Textbook)

Chemistry of Nucleic Acids (De Gruyter Textbook)
by: Harri Lönnberg (Author)
Publisher: De Gruyter
Edition: 2nd, Revised and Extended
Publication Date: 2024/9/23
Language: English
Print Length: 410 pages
ISBN-10: 3111325326
ISBN-13: 9783111325323
Book Description
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.
About the Author
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function. Read more