G Proteins

G Proteins

Author(s): Ravi Iyengar (Author), Lutz Birnbaumer

• Publisher: Academic Pr
• Publication Date: January 1, 1990
• Language: English
• Print length: 651 pages
• ISBN-10: 9780123774507
• ISBN-13: 9780123774507

Book Description

View on Amazon

{"@context":"https://schema.org","@type":"Book","name":"G Proteins","image":"https://m.media-amazon.com/images/I/01RmK+J4pJL._FMwebp_.gif","author":{"@type":"Person","name":"Ravi Iyengar (Author), Lutz Birnbaumer"},"publisher":{"@type":"Organization","name":"Academic Pr"},"datePublished":"January 1, 1990","isbn":"9780123774507","numberOfPages":651,"inLanguage":"English","description":"G Proteins is an introduction to one class of systems used for signal transduction at the cell surface, with emphasis on its utilization of a heterotrimeric GTP-binding protein (G protein) to mediate the transfer of information across the plasma membrane, from receptor to effector. Topics covered include the structure and function of G-protein a chains, ADP-ribosylation factor of adenylyl cyclase, and G protein-mediated effects on ionic channels. The organization of genes coding for G-protein a subunits in higher and lower eukaryotes is also discussed. This book is comprised of 25 chapters and begins with an overview of G proteins and their role in signal transduction. The next section focuses on the structural aspects of G proteins, with substantial emphasis on ? subunits. The mechanism of G protein coupling to effector systems is also considered, using the hormone-regulated adenylyl cyclase and light-regulated cGMP phosphodiesterase as models. Subsequent chapters deal with receptors and effector systems, together with the cellular functions that may be regulated by heterotrimeric G proteins. In particular, the interaction of insulin with G proteins is discussed, along with receptor regulation of cell calcium and phospholipase C activity. This monograph should be useful to students and scientists interested in G proteins.","url":"https://www.amazon.com/dp/0123774500/","bookFormat":"http://schema.org/EBook","additionalType":"http://schema.org/PDF","fileSize":"07 MB","accessibilityFeature":["login required","member access only"],"accessibilitySummary":"PDF version available to authenticated members only. File size: 07 MB."}