Annual Reports in Medicinal Chemistry, Volume 47
John E. Macor(Series Editor)
Book Description
Personal Essay
Paul S. Anderson
Peter R. Bernstein
M. Ross Johnson
I. Central Nervous System Diseases
Section Editor: Albert J. Robichaud; Sage Therapeutics, Inc. Cambridge, Massachusetts
Allen T. Hopper, Brian M. Campbell, Henry Kao, Sean A. Pintchovski and Roland G. W. Staal
Harrie J. M. Gijsen and François P. Bischoff
Sylvain Célanire, Guillaume Duvey, Sonia Poli and Jean-Philippe Rocher
Kamalesh B. Ruppa, Dalton King and Richard Olson
Lei Zhang and Anabella Villalobos
II. Cardiovascular and Metabolic Diseases
Section Editor: Andy Stamford, Merck Research Laboratories, Kenilworth, New Jersey
Donald J. P. Pinto, Pancras C. Wong, Robert M. Knabb and Ruth R. R. Wexler
Iyassu K. Sebhat and Robert W. Myers
Juan C. Jaen, Jay P. Powers and Tim Sullivan
Philip A. Carpino and David Hepworth
III. Inflammatory Pulmonary and Gastrointestinal Diseases
Section Editor: David S. Weinstein, Bristol-Myers Squibb R&D, Princeton, New Jersey
Alaric J. Dyckman
Gary Phillips and Michael Salmon
Robert O. Hughes, Alessandra Bartolozzi and Hidenori Takahashi
IV. Oncology
Section Editor: Shelli R. McAlpine, School of Chemistry, University of New South Wales, Sydney, Australia
Paul F. Richardson
Sean P. Brown and Joshua P. Taygerly
Vibhavari Sail and M. Kyle Hadden
Kazutomo Kinoshita, Nobuhiro Oikawa and Takuo Tsukuda
V. Infectious Diseases
Section Editor: John Primeau, Westford, Massachusetts
Jeremy Green, Upul Bandarage, Kate Luisi and Rene Rijnbrand
Pravin S. Shirude and Shahul Hameed
Robert Hamatake, Andrew Maynard and Wieslaw M. Kazmierski
VI. Topics in Biology
Section Editor: John Lowe, JL3Pharma LLC, Stonington, Connecticut
Victor S. Goldmacher, Thomas Chittenden, Ravi V. J. Chari, Yelena V. Kovtun and John M. Lambert
Indira Padmalayam and Mark J. Suto
Nuska Tschammer
Daniel D. Holsworth and Stefan Krauss
VII. Topics in Drug Design and Discovery
Section Editor: Peter R. Bernstein, PhaRmaB LLC, Rose Valley, Pennsylvania
Mark C. Noe and Adam M. Gilbert
P. Jeffrey Conn, Scott D. Kuduk and Darío Doller
VIII. Trends
Section Editor: Joanne Bronson, Bristol-Myers Squibb, Wallingford, Connecticut
Gregory T. Notte
- Reflections on Medicinal Chemistry at Merck, West Point
- My Path in Seeking New Medicines
- Tales of Drug Discovery
- Recent Developments in Targeting Neuroinflammation in Disease
- Secretase Inhibitors and Modulators as a Disease Modifying Approach Against Alzheimer’s Disease
- mGluR2 Activators and mGluR5 Blockers Advancing in the Clinic for Major CNS Disorders
- NMDA Antagonists of GluN2B Subtype and Modulators of GluN2A, GluN2C and GluN2D Subtypes - Recent Results and Developments
- Recent Advances in the Development of PET and SPECT Tracers for Brain Imaging
- Case History: EliquisTM(Apixaban), a Potent and Selective Inhibitor of Coagulation Factor Xa for the Prevention and Treatment of Thrombotic Diseases
- AMPK Activation in Health and Disease
- Type-2 Diabetes and Associated Co-Morbidities as an Inflammatory Syndrome
- Beyond PPARs & Metformin: New Insulin Sensitizers for the Treatment of Type 2 Diabetes
- Recent Advances in the Discovery and Development of Sphingosine-1-Phosphate-1 Receptor Agonists
- Bifunctional Compounds for the Treatment of COPD
- Inflammatory Targets for the Treatment of Atherosclerosis
- Nanotechnology Therapeutics in Oncology - Recent Developments and Future Outlook
- Small-Molecule Antagonists of Bcl-2 Family Proteins
- Notch Pathway Modulators as Anti-Cancer Chemotherapeutics
- Anaplastic Lymphoma Kinase (ALK) Inhibitors for the Treatment of ALK-Positive Cancers
- Recent Advances in the Discovery of Dengue Virus Inhibitors
- Non Fluoro-Quinolone Based Inhibitors of Mycobacterial Type II Topoisomerase as Potential Therapeutic Agents for TB
- HCV Inhibition Mediated through the Nonstructural Protein 5A (NS5A) Replication Complex
- Antibody-Drug Conjugates for Targeted Cancer Therapy
- 3D Cell Cultures: Mimicking in Vivo Tissues for Improved Predictability in Drug Discovery
- Virally Encoded G Protein-Coupled Receptors: Overlooked Therapeutic Opportunities?
- Recent Advances in Wnt/b-Catenin Pathway Small Molecule Inhibitors
- Targeted Covalent Enzyme Inhibitors
- Drug Design Strategies for GPCR Allosteric Modulators
- Progress in the Development of Non-ATP Competitive Protein Kinase Inhibitors for Oncology
Campbell McInnes - New Chemical Entities Entering Phase III Trials in 2011
- To Market, To Market - 2011
Joanne Bronson, Murali Dhar, William Ewing and Nils LonbergEditorial Reviews
Review
This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development."- ENZYMOLOGIA
From the Back Cover
Annual Reports in Medicinal Chemistryprovides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
Book Description
Paperback: 623 pages
Publisher: Academic Press; 1 edition (October 22, 2012)
Language: English
ISBN-10: 012396492X
ISBN-13: 97801239649221111 
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